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Index > Protein center > VCL(Gene name) > Pig
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  • VCL (Gene name),
  • Vinculin (Protein name ),  VINC_PIG from NCBI database.
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  • Antigen Annotation
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  • Gene name:
    VCL;
    Protein name:
    Vinculin;
    Alternative:
    Metavinculin;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Exhibits self-association properties. Interacts with NRAP, SORBS1 and TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin.
    Function:
    Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell junction adherens junction Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions.
    Protein Attributes:
    Sequence length:
    1135
    Sequence:
    50:
    MPVFHTRTIE | SILEPVAQQI | SHLVIMHEEG | EVDGKAIPDL | TAPVAAVQAA | 
    100:
    VSNLVRVGKE | TVQTTEDQIL | KRDMPPAFIK | VENACTKLVQ | AAQMLQSDPY | 
    150:
    SVPARDYLID | GSRGILSGTS | DLLLTFDEAE | VRKIIRVCKG | ILEYLTVAEV | 
    200:
    VETMEDLVTY | TKNLGPGMTK | MAKMIDERQQ | ELTHQEHRVM | LVNSMNTVKE | 
    250:
    LLPVLISAMK | IFVTTKNSKN | QGIEEALKNR | NFTVEKMSAE | INEIIRVLQL | 
    300:
    TSWDEDAWAS | KKDTEAMKRA | LASIDSKLNQ | AKGWLRDPTA | SPGDAGEQAI | 
    350:
    RQILDEAGKV | GELCAGKERR | EILGTCKMLG | QMTDQVADLR | ARGQGASPVA | 
    400:
    MQKAQQVSQG | LDVLTAKVEN | AARKLEAMTN | SKQSIAKKID | AAQNWLADPN | 
    450:
    GGPEGEEQIR | GALAEARKIA | ELCDDPKERD | DILRSLGEIS | ALTSKLADLR | 
    500:
    RQGKGDSPEA | RALAKQVATA | LQNLQTKTNR | AVANSRPAKA | AVHLEGKIEQ | 
    550:
    AQRWIDNPTV | DDRGVGQAAI | RGLVAEGHRL | ANVMMGPYRQ | DLLAKCDRVD | 
    600:
    QLTAQLADLA | ARGEGESPQA | RALASQLQDS | LKDLKARMQE | AMTQEVSDVF | 
    650:
    SDTTTPIKLL | AVAATAPPDA | PNREEVFDER | AANFENHSGR | LGATAEKAAA | 
    700:
    VGTANKSTVE | GIQASVKTAR | ELTPQVVSAA | RILLRNPGNQ | AAYEHFETMK | 
    750:
    NQWIDNVEKM | TGLVDEAIDT | KSLLDASEEA | IKKDLDKCKV | AMANIQPQML | 
    800:
    VAGATSIARR | ANRILLVAKR | EVENSEDPKF | REAVKAASDE | LSKTISPMVM | 
    850:
    DAKAVAGNIS | DPGLQKSFLD | SGYRILGAVA | KVREAFQPQE | PDFPPPPPDL | 
    900:
    EQLRLTDELA | PPKPPLPEGE | VPPPRPPPPE | EKDEEFPEQK | AGEVINQPMM | 
    950:
    MAARQLHDEA | RKWSSKPGNP | AAKVGIGVVA | EADAADAVGF | PVPSDMEDDY | 
    1000:
    EPELLLMPSS | QPVNQPILAA | AQSLHREATK | WSSKGNDIIA | AAKRMALLMA | 
    1050:
    EMSRLVRGGS | GTKRALIQCA | KDIAKASDEV | TRLAKEVAKQ | CTDKRIRTNL | 
    1100:
    LQVCERIPTI | STQLKILSTV | KATMLGRTNI | SDEESEQATE | MLVHNAQNLM | 
    1135:
    QSVKETVREA | EAASIKIRTD | AGFTLRWVRK | TPWYQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Vinculin
    Cat.:
    E1839r
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    96T
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    ELISA Kit for Pig Vinculin
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    E1839c
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    ELISA Kit for Pig Vinculin
    Cat.:
    E1839p
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    Packing:
    96T
    ELISA Kit for Pig Vinculin
    Cat.:
    E1839h
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    96T
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    ELISA Kit for Pig Vinculin
    Cat.:
    E1839m
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    Packing:
    96T
    CLIA Kit for Pig Vinculin
    Cat.:
    U1839h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig Vinculin
    Cat.:
    U1839p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Vinculin
    Cat.:
    U1839c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Vinculin
    Cat.:
    U1839r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Vinculin
    Cat.:
    U1839m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig Vinculin
    Cat.:
    P1839Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Vinculin
    Cat.:
    P1839Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Vinculin
    Polyclonal Antibody for Pig Vinculin
    Polyclonal Antibody for Pig Vinculin
    Cat.:
    P1839Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig Vinculin
    Monoclonal Antibody for Pig Vinculin
    Monoclonal Antibody for Pig Vinculin
    Monoclonal Antibody for Pig Vinculin
    Monoclonal Antibody for Pig Vinculin
    Protein for Pig Vinculin
    Protein for Pig Vinculin
    Protein for Pig Vinculin
    Protein for Pig Vinculin
    Protein for Pig Vinculin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Analysis of porcine vinculin gene as a candidate gene for carcass traits."
      Ponsuksili S. , Wimmers K. , Schmoll F. , Schellander K.
      Submitted (1999-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Longissimus muscle.
    2. 2.
      "Porcine vinculin and metavinculin differ by a 68-residue insert located close to the carboxy-terminal part of the molecule."
      Gimona M. , Small J.V. , Moeremans M. , van Damme J. , Puype M. , Vandekerckhove J.
      EMBO J.7:2329-2334(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-21; 244-260; 496-512 AND 852-1006
    3. 3.
      "Variable and constant regions in the C-terminus of vinculin and metavinculin. Cloning and expression of fragments in E. coli."
      Strasser P. , Gimona M. , Herzog M. , Geiger B. , Small J.V.
      FEBS Lett.317:189-194(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 912-1135 (ISOFORM 2)
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