Protein name:
Vinculin ;
Alternative:
Metavinculin ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Exhibits self-association properties. Interacts with NRAP, SORBS1 and TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin.
Function:
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Subcellular Location:
Cytoplasm
cytoskeleton
Cell junction
adherens junction
Cell membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions.
Protein Attributes:
50:
MPVFHTRTIE | SILEPVAQQI | SHLVIMHEEG | EVDGKAIPDL | TAPVAAVQAA |
100:
VSNLVRVGKE | TVQTTEDQIL | KRDMPPAFIK | VENACTKLVQ | AAQMLQSDPY |
150:
SVPARDYLID | GSRGILSGTS | DLLLTFDEAE | VRKIIRVCKG | ILEYLTVAEV |
200:
VETMEDLVTY | TKNLGPGMTK | MAKMIDERQQ | ELTHQEHRVM | LVNSMNTVKE |
250:
LLPVLISAMK | IFVTTKNSKN | QGIEEALKNR | NFTVEKMSAE | INEIIRVLQL |
300:
TSWDEDAWAS | KKDTEAMKRA | LASIDSKLNQ | AKGWLRDPTA | SPGDAGEQAI |
350:
RQILDEAGKV | GELCAGKERR | EILGTCKMLG | QMTDQVADLR | ARGQGASPVA |
400:
MQKAQQVSQG | LDVLTAKVEN | AARKLEAMTN | SKQSIAKKID | AAQNWLADPN |
450:
GGPEGEEQIR | GALAEARKIA | ELCDDPKERD | DILRSLGEIS | ALTSKLADLR |
500:
RQGKGDSPEA | RALAKQVATA | LQNLQTKTNR | AVANSRPAKA | AVHLEGKIEQ |
550:
AQRWIDNPTV | DDRGVGQAAI | RGLVAEGHRL | ANVMMGPYRQ | DLLAKCDRVD |
600:
QLTAQLADLA | ARGEGESPQA | RALASQLQDS | LKDLKARMQE | AMTQEVSDVF |
650:
SDTTTPIKLL | AVAATAPPDA | PNREEVFDER | AANFENHSGR | LGATAEKAAA |
700:
VGTANKSTVE | GIQASVKTAR | ELTPQVVSAA | RILLRNPGNQ | AAYEHFETMK |
750:
NQWIDNVEKM | TGLVDEAIDT | KSLLDASEEA | IKKDLDKCKV | AMANIQPQML |
800:
VAGATSIARR | ANRILLVAKR | EVENSEDPKF | REAVKAASDE | LSKTISPMVM |
850:
DAKAVAGNIS | DPGLQKSFLD | SGYRILGAVA | KVREAFQPQE | PDFPPPPPDL |
900:
EQLRLTDELA | PPKPPLPEGE | VPPPRPPPPE | EKDEEFPEQK | AGEVINQPMM |
950:
MAARQLHDEA | RKWSSKPGNP | AAKVGIGVVA | EADAADAVGF | PVPSDMEDDY |
1000:
EPELLLMPSS | QPVNQPILAA | AQSLHREATK | WSSKGNDIIA | AAKRMALLMA |
1050:
EMSRLVRGGS | GTKRALIQCA | KDIAKASDEV | TRLAKEVAKQ | CTDKRIRTNL |
1100:
LQVCERIPTI | STQLKILSTV | KATMLGRTNI | SDEESEQATE | MLVHNAQNLM |
1135:
QSVKETVREA | EAASIKIRTD | AGFTLRWVRK | TPWYQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Chicken
Pig
Human
Mouse
ELISA Kit for Pig Vinculin
ELISA Kit for Pig Vinculin
ELISA Kit for Pig Vinculin
ELISA Kit for Pig Vinculin
ELISA Kit for Pig Vinculin
CLIA Kit for Pig Vinculin
CLIA Kit for Pig Vinculin
CLIA Kit for Pig Vinculin
CLIA Kit for Pig Vinculin
CLIA Kit for Pig Vinculin
Polyclonal Antibody for Pig Vinculin
Polyclonal Antibody for Pig Vinculin
Polyclonal Antibody for Pig Vinculin
Polyclonal Antibody for Pig Vinculin
Polyclonal Antibody for Pig Vinculin
Monoclonal Antibody for Pig Vinculin
Monoclonal Antibody for Pig Vinculin
Monoclonal Antibody for Pig Vinculin
Monoclonal Antibody for Pig Vinculin
Monoclonal Antibody for Pig Vinculin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Longissimus muscle .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-21; 244-260; 496-512 AND 852-1006
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 912-1135 (ISOFORM 2)